Elevated serum levels of adiponectin associated with a lower risk of coronary heart disease
Document Actions
31/12/2006
Numerous studies indicate an inverse relationship between adiponectin and obesity or coronary heart disease (CHD) prevalence. In a population-based cohort study conducted in Sweden, 832 healthy men aged 70 years were followed up for 10.4 years, using national registry data. Baseline measurements included anthropometry, blood pressure, smoking, serum lipids, euglycaemic insulin clamp and fasting serum adiponectin. Outcome measures were defined as death or first time hospitalization for coronary heart disease. In a multivariable analysis, serum adiponectin was shown to be associated with a lower risk for CHD (hazard ratio =0.81; CI=0.66-0.99), independently of other well-known risk factors.
Web address
