Biomarkers

  • The therapeutic modulation of atherogenic dyslipidemia and inflammatory markers in the metabolic syndrome: what is the clinical relevance?
    (Rizzo M, et al. Acta Diabetol. 2009 Mar;46(1):1-11. Epub 2008 Oct 17.)
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Cancer

  • Components of metabolic syndrome and metachronous colorectal neoplasia.
    (Ashbeck EL, et al. Cancer Epidemiol Biomarkers Prev. 2009 Mar 24. [Epub ahead of print])
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  • Components of the metabolic syndrome and risk of prostate cancer: the HUNT 2 cohort, Norway.
    (Martin RM, et al. Cancer Causes Control. 2009 Mar 11. [Epub ahead of print])
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  • Metabolic syndrome and cancer.
    (Pothiwala P, et al. Metab Syndr Relat Disord. 2009 Mar 14. [Epub ahead of print])
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  • Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis.
    (Paradis V, et al. Hepatology. 2009 Mar;49(3):851-9.)
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Cardiovascular Disease

  • Altered mechanism of adenosine-induced coronary arteriolar dilation in early-stage metabolic syndrome.
    (Bender SB, et al. Exp Biol Med (Maywood). 2009 Mar 23. [Epub ahead of print])
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  • Impaired left ventricular systolic and diastolic function in patients with metabolic syndrome as assessed by strain and strain rate imaging.
    (Gong HP, et al. Diabetes Res Clin Pract. 2009 Mar;83(3):300-7. Epub 2009 Jan 23.)
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  • Small dense low-density lipoprotein in familial combined hyperlipidemia: Independent of metabolic syndrome and related to history of cardiovascular events.
    (Pauciullo P, et al. Atherosclerosis. 2009 Mar;203(1):320-4. Epub 2008 Jul 12.)
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  • Oxidative stress and metabolic syndrome.
    (Roberts CK, et al. Life Sci. 2009 Mar 9. [Epub ahead of print])
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  • Metabolic Syndrome and All-Cause and Cardiovascular Disease Mortality.
    (Saito I, et al. Circ J. 2009 Mar 12. [Epub ahead of print])
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  • The impact of metabolic syndrome on left ventricular function: evaluated by using the index of myocardial performance.
    (Turhan H, et al. Int J Cardiol. 2009 Mar 6;132(3):382-6. Epub 2008 Feb 11.)
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Defining the Metabolic Syndrome

  • Is a unified definition of metabolic syndrome needed? Comparison of three definitions of metabolic syndrome in 60-Year-Old men and women.
    (Carlsson AC, et al. Metab Syndr Relat Disord. 2009 Mar 14. [Epub ahead of print])
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  • The metabolic syndrome: in need of a global mission statement.
    (Cameron AJ, et al. Diabet Med. 2009 Mar;26(3):306-9.)
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  • Is the metabolic syndrome a discrete diagnostic category or the end of a continuum? Taxometric evidence for dimensionality in the National Health and Nutrition Examination Survey 1999-2004.
    (Ingram DG. Ann Epidemiol. 2009 Mar;19(3):143-7.)
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Diabetes

  • Serum adiponectin as a useful marker for metabolic syndrome in type 2 diabetic patients.
    (Yun JE, et al. Diabetes Metab Res Rev. 2009 Mar;25(3):259-65.)
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  • Glycaemic variability and inflammation in subjects with metabolic syndrome.
    (Buscemi S, et al. Acta Diabetol. 2009 Mar;46(1):55-61. Epub 2008 Sep 26.)
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  • The association between pulse wave velocity and metabolic syndrome and adiponectin in patients with impaired fasting glucose: Cardiovascular risks and adiponectin in IFG.
    (Nam JS, et al. Diabetes Res Clin Pract. 2009 Mar 2. [Epub ahead of print])
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  • Cardiovascular risk factors characteristic for the metabolic syndrome in adult patients with type 1 diabetes.
    (Nádas J, et al. Exp Clin Endocrinol Diabetes. 2009 Mar;117(3):107-12. Epub 2009 Mar 10.)
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Diet, Nutrition & Metabolism

  • Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study.
    (Chen J, et al. Lancet. 2009 Mar 7;373(9666):829-35. Epub 2009 Feb 14.)
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  • Relationship between long-term coffee consumption and components of the metabolic syndrome: the Amsterdam Growth and Health Longitudinal Study.
    (Balk L, et al. Eur J Epidemiol. 2009 Mar 10. [Epub ahead of print])
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  • Carbohydrate-restricted versus low-glycemic-index diets for the treatment of insulin resistance and metabolic syndrome.
    (Wood RJ, et al. Nutr Rev. 2009 Mar;67(3):179-83.)
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  • Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome.
    (Heinonen MV, et al. Nutr Metab Cardiovasc Dis. 2009 Mar 9. [Epub ahead of print])
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  • Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome.
    (Bitto A, et al. J Endocrinol. 2009 Mar;200(3):367-76. Epub 2008 Dec 9.)
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  • Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.
    (Delibegovic M, et al. Diabetes. 2009 Mar;58(3):590-9. Epub 2008 Dec 15.)
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  • Dietary carotenoid intake is associated with lower prevalence of metabolic syndrome in middle-aged and elderly men.
    (Sluijs I, et al. J Nutr. 2009 Mar 25. [Epub ahead of print])
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Drug Therapy

  • Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study.
    (Scott R, et al. Diabetes Care. 2009 Mar;32(3):493-8. Epub 2008 Nov 4.)
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  • Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia.
    (Lee IT, et al. Metabolism. 2009 Mar;58(3):416-20.)
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  • Effects of rosuvastatin and atorvastatin on low-density and high-density lipoprotein particle concentrations in patients with metabolic syndrome: A randomized, double-blind, controlled study.
    (Rosenson RS, et al. Diabetes Care. 2009 Mar 5. [Epub ahead of print])
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  • Effect of fenofibrate on adiponectin and inflammatory biomarkers in metabolic syndrome patients.
    (Rosenson RS. Obesity (Silver Spring). 2009 Mar;17(3):504-9. Epub 2008 Nov 20.)
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  • Exenatide improves hypertension in a rat model of the metabolic syndrome.
    (Laugero KD, et al. Metab Syndr Relat Disord. 2009 Mar 25. [Epub ahead of print])
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Epidemiology

  • Prevalence of metabolic syndrome according to Adult Treatment Panel III and International Diabetes Federation Criteria: A population-based study.
    (Bener A, et al. Metab Syndr Relat Disord. 2009 Mar 25. [Epub ahead of print])
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  • The metabolic syndrome: A critical appraisal based on the cuore epidemiologic study.
    (Giampaoli S, et al. Prev Med. 2009 Mar 31. [Epub ahead of print])
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  • Asian ethnicity and the prevalence of metabolic syndrome in the osteoarthritic total knee arthroplasty population.
    (Gandhi R, et al. J Arthroplasty. 2009 Mar 9. [Epub ahead of print])
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  • Metabolic syndrome is associated with venous thromboembolism in the Korean population.
    (Jang MJ, et al. Arterioscler Thromb Vasc Biol. 2009 Mar;29(3):311-5.)
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  • Factor analysis of the individual components of the metabolic syndrome among elderly identifies two factors with different survival patterns-A population-based study.
    (Ohrvik J, et al. Metab Syndr Relat Disord. 2009 Mar 14. [Epub ahead of print])
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  • The first nationwide study of the prevalence of the metabolic syndrome and optimal cut-off points of waist circumference in the Middle East: The national survey of risk factors for non-communicable diseases of Iran.
    (Delavari A, et al. Diabetes Care. 2009 Mar 11. [Epub ahead of print])
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  • Proposed criteria for metabolic syndrome in Japanese based on prospective evidence: the Hisayama study.
    (Doi Y, et al. Stroke. 2009 Apr;40(4):1187-94. Epub 2009 Mar 5.)
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  • Metabolic syndrome and its components as predictors of incident type 2 diabetes mellitus in an Aboriginal community.
    (Ley SH, et al. CMAJ. 2009 Mar 17;180(6):617-24.)
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  • Association of smoking with aortic wave reflection and central systolic pressure and metabolic syndrome in normotensive Japanese men.
    (Minami J, et al. Am J Hypertens. 2009 Mar 26. [Epub ahead of print])
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  • Prevalence of diabetes, metabolic syndrome, and cardiovascular risk factors in US Asian Indians: results from a national study.
    (Misra R, et al. J Diabetes Complications. 2009 Mar 18. [Epub ahead of print])
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  • The prevalence of impaired glucose metabolism in Hispanics with two or more risk factors for metabolic syndrome in the primary care setting.
    (Neira CP, et al. J Am Acad Nurse Pract. 2009 Mar;21(3):173-8.)
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Exercise & Physical Activity

  • Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity.
    (Haram PM, et al. Cardiovasc Res. 2009 Mar 1;81(4):723-32. Epub 2008 Dec 1.)
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  • Effects of exercise training intensity on nocturnal growth hormone secretion in obese adults with the metabolic syndrome.
    (Irving BA, et al. J Clin Endocrinol Metab. 2009 Mar 24. [Epub ahead of print])
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  • Physical activity and the metabolic syndrome in elderly German men and women: results from the population-based KORA survey.
    (Hahn V, et al. Diabetes Care. 2009 Mar;32(3):511-3. Epub 2008 Dec 15.)
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  • Sedentary behaviour, physical activity and a continuous metabolic syndrome risk score in adults.
    (Wijndaele K, et al. Eur J Clin Nutr. 2009 Mar;63(3):421-9. Epub 2007 Oct 31.)
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  • Impact of short-duration lifestyle intervention in collaboration with general practitioners in patients with the metabolic syndrome.
    (Bihan H, et al. Diabetes Metab. 2009 Mar 17. [Epub ahead of print])
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Genetics

  • The -1131T>C SNP of the APOA5 gene modulates response to fenofibrate treatment in patients with the metabolic syndrome: A postprandial study.
    (Cardona F, et al. Atherosclerosis. 2009 Mar 11. [Epub ahead of print])
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  • Genetic variants at the PDZ-interacting domain of the scavenger receptor class B type I interact with diet to influence the risk of metabolic syndrome in obese men and women.
    (Junyent M, et al. J Nutr. 2009 Mar 25. [Epub ahead of print])
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  • Does genetic variation in the Delta6-desaturase promoter modify the association between alpha-linolenic acid and the prevalence of metabolic syndrome?
    (Truong H, et al. Am J Clin Nutr. 2009 Mar;89(3):920-5. Epub 2009 Jan 14.)
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  • Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome.
    (Yoshida T, et al. Genomics. 2009 Mar;93(3):221-6. Epub 2008 Dec 6.)
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Hypertension

  • Metabolic syndrome and biventricular hypertrophy in essential hypertension.
    (Cuspidi C, et al. J Hum Hypertens. 2009 Mar;23(3):168-75. Epub 2008 Sep 18.)
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  • Association of metabolic syndrome and blood pressure nondipping profile in untreated hypertension.
    (Hermida RC, et al. Am J Hypertens. 2009 Mar;22(3):307-13. Epub 2009 Jan 8.)
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Innovative Techniques & Modeling

  • Connecting lipid droplet biology and the metabolic syndrome.
    (Lay SL, et al. Prog Lipid Res. 2009 Mar 20. [Epub ahead of print])
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Metabolic Syndrome in Men

  • Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome.
    (Demir O, et al. Aging Male. 2009 Mar;12(1):29-34.)
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  • Penile vascular impairment in erectile dysfunction patients with metabolic syndrome: penile Doppler ultrasound findings.
    (Demir O, et al. Urol Int. 2009;82(2):175-8. Epub 2009 Mar 19.)
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Metabolic Syndrome in Women

  • Calcium intake is inversely associated with metabolic syndrome in postmenopausal women: Korea National Health and Nutrition Survey, 2001 and 2005.
    (Cho GJ, et al. Menopause. 2009 Mar 18. [Epub ahead of print])
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  • Thyroid stimulating hormone is associated with metabolic syndrome in euthyroid postmenopausal women.
    (Park HT, et al. Maturitas. 2009 Mar 20;62(3):301-5. Epub 2009 Feb 27.)
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  • The metabolic syndrome and development of cognitive impairment among older women.
    (Yaffe K, et al. Arch Neurol. 2009 Mar;66(3):324-8.)
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  • Clinical spectrum of premature pubarche: Links to metabolic syndrome and ovarian hyperandrogenism.
    (Ibáńez L, et al. Rev Endocr Metab Disord. 2009 Mar;10(1):63-76.)
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Non-Alcholic Fatty Liver Disease

  • Hepatitis C, human immunodeficiency virus and metabolic syndrome: interactions.
    (Kotler DP. Liver Int. 2009 Mar;29 Suppl 2:38-46.)
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  • Liver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease cases.
    (Uslusoy HS, et al. World J Gastroenterol. 2009 Mar 7;15(9):1093-8.)
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  • Metabolic syndrome, non-alcoholic fatty liver disease and hepatitis C virus: impact on disease progression and treatment response.
    (Younossi ZM, et al. Liver Int. 2009 Mar;29 Suppl 2:3-12.)
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  • NAFLD as a risk factor for the development of diabetes and the metabolic syndrome: an eleven-year follow-up study.
    (Adams LA, et al. Am J Gastroenterol. 2009 Apr;104(4):861-7. Epub 2009 Mar 17.)
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Obesity

  • Lung function impairment and metabolic syndrome: the critical role of abdominal obesity.
    (Leone N, et al. Am J Respir Crit Care Med. 2009 Mar 15;179(6):509-16. Epub 2009 Jan 8.)
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  • Visceral obesity is associated with the metabolic syndrome and elevated plasma retinol binding protein-4 level in obstructive sleep apnea syndrome.
    (Makino S, et al. Horm Metab Res. 2009 Mar;41(3):221-6. Epub 2008 Nov 10.)
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  • Obesity and the metabolic syndrome in a student cohort from Southern Italy.
    (Noto D, et al. Nutr Metab Cardiovasc Dis. 2009 Mar 2. [Epub ahead of print])
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  • The metabolic syndrome and behavioral correlates in obese patients with binge eating disorder.
    (Roehrig M, et al. Obesity (Silver Spring). 2009 Mar;17(3):481-6. Epub 2008 Dec 11.)
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  • Body mass index, metabolic syndrome and carotid atherosclerosis.
    (Irace C, et al. Coron Artery Dis. 2009 Mar;20(2):94-9.)
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Pediatrics

  • Parental history of type 2 diabetes mellitus, metabolic syndrome, and cardiometabolic risk factors in Asian Indian adolescents.
    (Anjana RM, et al. Metabolism. 2009 Mar;58(3):344-50.)
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  • Homeostasis model assessment of insulin resistance*body mass index interactions at ages 9 to 10 years predict metabolic syndrome risk factor aggregate score at ages 18 to 19 years: a 10-year prospective study of black and white girls.
    (Morrison JA, et al. Metabolism. 2009 Mar;58(3):290-5.)
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  • Low birth weight and early weight gain in the metabolic syndrome: consequences for infant nutrition.
    (Vaag A. Int J Gynaecol Obstet. 2009 Mar;104 Suppl 1:S32-4. Epub 2009 Jan 19.)
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Psychological Disorders

  • Association between metabolic syndrome and depressive symptoms in middle-aged adults: results from the Whitehall II study.
    (Akbaraly TN, et al. Diabetes Care. 2009 Mar;32(3):499-504. Epub 2008 Dec 23.)
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Renal Function

  • Kidney pathological changes in metabolic syndrome: A cross-sectional study.
    (Alexander MP, et al. Am J Kidney Dis. 2009 Mar 31. [Epub ahead of print])
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  • Metabolic syndrome attenuates effect of chronic kidney disease on prevalence of coronary disease in men referred for stress imaging study.
    (Kamalesh M, et al. Clin Nephrol. 2009 Mar;71(3):255-62.)
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Risk Factors

  • Association between metabolic syndrome and nephrolithiasis in an inpatient population in southern Italy: role of gender, hypertension and abdominal obesity.
    (Rendina D, et al. Nephrol Dial Transplant. 2009 Mar;24(3):900-6. Epub 2008 Oct 3.)
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  • Serum gamma-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria.
    (Jo SK, et al. Clin Chim Acta. 2009 Mar 28. [Epub ahead of print])
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  • Metabolic syndrome is an independent risk factor for stroke and acute renal failure after coronary artery bypass grafting.
    (Kajimoto K, et al. J Thorac Cardiovasc Surg. 2009 Mar;137(3):658-63.)
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  • Metabolic syndrome and risk factors for cardiovascular disease: are nonagenarians protected?
    (Frisard MI, et al. Age (Dordr). 2009 Mar;31(1):67-75. Epub 2009 Jan 31.)
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  • A cross-sectional study of intima-media thickness, ethnicity, metabolic syndrome, and cardiovascular risk in 2268 study participants.
    (Adolphe A, et al. Mayo Clin Proc. 2009 Mar;84(3):221-8.)
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  • Metabolic syndrome in older subjects: coincidence or clustering?
    (Bo M, et al. Arch Gerontol Geriatr. 2009 Mar-Apr;48(2):146-50. Epub 2008 Feb 19.)
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  • Is having a family history of type 2 diabetes or cardiovascular disease a predictive factor for metabolic syndrome?
    (Dunkley AJ, et al. Prim Care Diabetes. 2009 Feb;3(1):49-56. Epub 2009 Mar 5.)
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  • Migraine in metabolic syndrome.
    (Guldiken B, et al. Neurologist. 2009 Mar;15(2):55-8.)
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  • The metabolic syndrome in elderly individuals is associated with greater muscular, but not elastic arterial stiffness, independent of low-grade inflammation, endothelial dysfunction or insulin resistance-The Hoorn Study.
    (Henry RM, et al. J Hum Hypertens. 2009 Mar 12. [Epub ahead of print])
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  • First acute gout attacks commonly precede features of the metabolic syndrome.
    (Hernández-Cuevas CB, et al. J Clin Rheumatol. 2009 Mar;15(2):65-7.)
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  • Defensiveness and metabolic syndrome: impact of sex and age.
    (Lévesque K, et al. Biol Psychol. 2009 Mar;80(3):354-60. Epub 2008 Dec 27.)
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  • Metabolic syndrome in rheumatological diseases.
    (Pereira RM, et al. Autoimmun Rev. 2009 Mar;8(5):415-9. Epub 2009 Jan 23.)
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  • Castration modifies aortic vasoreactivity and serum fatty acids in a sucrose-fed rat model of metabolic syndrome.
    (Perez I, et al. Heart Vessels. 2009 Mar;24(2):147-55. Epub 2009 Apr 1.)
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  • High-molecular-weight adiponectin is a predictor of progression to metabolic syndrome: a population-based 6-year follow-up study in Japanese men.
    (Seino Y, et al. Metabolism. 2009 Mar;58(3):355-60.)
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  • Association between primary hypothyroidism and metabolic syndrome and the role of C reactive protein: a cross-sectional study from South India.
    (Shantha GP, et al. Thyroid Res. 2009 Mar 9;2(1):2.)
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  • IGF-I/IGFBP-3 ratio: a mechanistic insight into the metabolic syndrome.
    (Sierra-Johnson J, et al. Clin Sci (Lond). 2009 Mar;116(6):507-12.)
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  • Metabolic syndrome and risk of recurrence of atrial fibrillation after catheter ablation.
    (Tang RB, et al. Circ J. 2009 Mar;73(3):438-43. Epub 2009 Jan 28.)
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  • Are lower urinary tract symptoms influenced by metabolic syndrome?
    (Temml C, et al. Urology. 2009 Mar;73(3):544-8. Epub 2009 Jan 1.)
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  • Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
    (Trřseid M, et al. Diabetes Care. 2009 Mar;32(3):486-92. Epub 2008 Dec 17.)
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  • Circulating oxidized LDL, measured with FOH1a/DLH3 antibody, is associated with metabolic syndrome and the coronary heart disease risk score in healthy Japanese.
    (Ueba T, et al. Atherosclerosis. 2009 Mar;203(1):243-8. Epub 2008 Jun 3.)
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  • Presence of the metabolic syndrome is not a better predictor of cardiovascular disease than the sum of its components in HIV-infected individuals: data collection on adverse events of anti-HIV drugs (D:A:D) study.
    (Worm SW, et al. Diabetes Care. 2009 Mar;32(3):474-80. Epub 2008 Dec 3.)
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Screening

  • Metabolic syndrome, cardiovascular risk and screening for subclinical atherosclerosis.
    (Malik S, et al. Expert Rev Cardiovasc Ther. 2009 Mar;7(3):273-80.)
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  • The metabolic syndrome is not a sensible tool for predicting the risk of coronary heart disease.
    (Woodward M, et al. Eur J Cardiovasc Prev Rehabil. 2009 Mar 19. [Epub ahead of print])
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  • Longitudinal paths to the metabolic syndrome: Can the incidence of the metabolic syndrome be predicted? The Baltimore Longitudinal Study of Aging.
    (Scuteri A, et al. J Gerontol A Biol Sci Med Sci. 2009 Mar 6. [Epub ahead of print])
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Stroke

  • Adenosine, an identified active component from the Driselase-treated fraction of rice bran, is effective at improving metabolic syndrome in stroke-prone spontaneously hypertensive rats.
    (Ardiansyah, et al. J Agric Food Chem. 2009 Mar 25;57(6):2558-64.)
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Framingham Risk Assessment Tool
Estimates 10-year risk of developing hard CHD
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Procam Risk Calculator
Estimates your risk of a heart attack (myocardial infarction) within the next 10 years based upon data of the PROCAM Study
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SCORE
(European High Risk Chart)

Estimates 10 year risk of fatal CVD in high risk regions of Europe by gender, age, systolic blood pressure, total cholesterol and smoking status.
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UKPDS Risk Engine
The UKPDS Risk Engine is a type 2 diabetes specific risk calculator based on 53,000 patients years of data from the UK Prospective Diabetes Study, which also provides an approximate 'margin of error' for each estimate.
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Coordinated by Dr. Scott Grundy, Past-President of the IAS